Journal
BEHAVIORAL NEUROSCIENCE
Volume 114, Issue 3, Pages 647-651Publisher
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/0735-7044.114.3.647
Keywords
-
Categories
Funding
- NIMH NIH HHS [MH-11627-02] Funding Source: Medline
Ask authors/readers for more resources
The present study examined the effects of bilateral intra-amygdaloid infusions of the D-2 receptor antagonist, eticlopride, on the acquisition and expression of Pavlovian fear conditioning as measured by freezing to acoustic and background contextual stimuli in the rat. Infusions of eticlopride before acquisition or before both acquisition and retention testing significantly attenuated conditioned freezing to tone presentations during the retention test 24 hr later. No effects, however, were observed on freezing that emerged during acquisition. Furthermore. these effects were not attributable to state-dependent learning effects or alterations in baseline activity or shock reactivity. In conclusion, these results suggest that amygdaloid dopamine transmission at D-2 receptors contributes to the formation and/or consolidation of fear memories.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available