Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 12, Issue 3, Pages 346-350Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(00)00098-3
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- NIGMS NIH HHS [GM45443] Funding Source: Medline
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Recent results have identified a family of Lsm (Like Sm) proteins that are related to the Sm protein family. Seven Lsm proteins form a complex, which interacts with the U6 snRNA and functions in splicing. In addition. a different complex of Lsm proteins interacts with cytoplasmic mRNA and promotes its turnover. These diverse functions of Lsm proteins suggest that they are important modulators of RNA biogenesis and function.
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