4.4 Article

Supratentorial primitive neuroectodermal tumours: diffusion-weighted MRI

Journal

NEURORADIOLOGY
Volume 42, Issue 6, Pages 393-398

Publisher

SPRINGER VERLAG
DOI: 10.1007/s002340000318

Keywords

primitive neuroectodermal tumours; brain, neoplasms; magnetic resonance imaging, diffusion weighted

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We report the clinical and pathological findings of supratentorial primitive neuroectodermal tumours (PNETs). These are rare, poorly differentiated, highly malignant neoplasms occurring primarily in young individuals. They frequently show dissemination to the spinal cord and sometimes also beyond neuraxis. Preoperative radiological diagnosis is difficult, due to the nonspecific CT and MRI characteristics. Our findings indicate that diffusion-weighted imaging (DWI) can be used to show the solid portion of the tumour preoperatively and to monitor post-surgical recovery. We describe the MRI findings in three patients with histologically confirmed supratentorial PNET, focussing on the role of DWI for improving the specificity of radiological diagnosis.

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