Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 66, Issue 6, Pages 2664-2667Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.66.6.2664-2667.2000
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Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones. Cultures grown in sucrose-peptone broth were dosed with enrofloxacin. After 21 days, 22% of the enrofloxacin remained. Three metabolites were Identified: enrofloxacin N-oxide (62% of the total absorbance), N-acetylciprofloxacin (8.0%), and desethylene-enrofloxacin (3.5%).
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