Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 70, Issue 3, Pages 213-217Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0378-8741(99)00169-5
Keywords
Ligustrum vulgare; Phillyrea latifolia; Mediterranean ethnomedicine; flavones; anti-complementary activity
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Polar fractions and flavones isolated from methanolic extracts of the leaves of Ligustrum vulgare and Phillyrea latifolia (Oleaceae), whose popular use as an anti inflammatory is well-known in Mediterranean historical medicine and ethnobotany, showed significant in vitro complement inhibiting effect on the classical pathway of the complement system. Among the isolated flavonoidic structures, apigenin-7-O-glucoside, apigenin-7-O-rutinoside, luteolin-4'-O-glucoside, luteolin-7-O-glucoside and ligustroflavone presented remarkable activity. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
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