Journal
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Volume 14, Issue 5, Pages 556-567Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.bbmt.2008.02.019
Keywords
acute myeloid leukemia; hematopoietic stem cell transplantation; bone marrow transplantation; reduced intensity; acute leukemia; graft-versus-leukemia effect
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Hematopoietic stem cell transplantation (HSCT) is an integral part of the treatment of many patients with acute myeloid leukemia (AML). Despite extensive study, the appropriate role and timing of allogeneic and autologous transplantation in AML are poorly defined. This review critically analyzes the extensive literature, focusing on the recent advances, and provides practical recommendations for the use of HSCT in AML. (C) 2008 American Society for Blood and Marrow Transplantation.
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