Journal
INFECTION AND IMMUNITY
Volume 68, Issue 6, Pages 3768-3771Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.68.6.3768-3771.2000
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Mutation of waaN, a gene involved in lipid A biosynthesis, reduced enteropathogenic responses induced by Salmonella enterica serovar Typhimurium in bovine ligated ileal loops. However, the secretion of key virulence determinants was also reduced, and therefore the reduction in enteropathogenicity cannot be solely attributed to a reduction in biological activity of lipid A.
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