4.7 Article

New approach to the study of particle-surface adhesion using atomic force microscopy

Journal

JOURNAL OF COLLOID AND INTERFACE SCIENCE
Volume 226, Issue 1, Pages 185-188

Publisher

ACADEMIC PRESS INC
DOI: 10.1006/jcis.2000.6801

Keywords

adhesion; AFM; colloidal probe; particle-surface adhesion; spatial variation of adhesion; adhesion force; lactose; gelatin capsule

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The colloidal probe technique is commonly employed to determine the adhesion force between a particle and a solid surface. Characterization of the adhesion of a particle across a surface can be as important, if not more so, as the determination of an average value for the adhesion. Unfortunately, the measurement of the variation in adhesion can be difficult at best. A new approach for studying particle-surface adhesion based on the force-volume technique is presented. Upon combining the force-volume technique with a colloidal probe, not only is it possible to determine the average adhesion force, but an image of the spatial variation of the adhesion can also be obtained. This method is envisioned to have great potential for examining and analyzing the adhesion behavior in complex natural and technological systems. (C) 2000 Academic Press.

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