Journal
FORENSIC SCIENCE INTERNATIONAL
Volume 110, Issue 3, Pages 199-206Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0379-0738(00)00177-8
Keywords
time of death; immunohistochemistry; detection of thyroglobulin; thyroid gland
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To improve the possibilities to delimit the time of death after longer laytime it was examined if this is possible by immunohistochemical detection of thyroglobulin. The results show that in our examination material the colloid and the follicular cells of the thyroid glands of up to 5-day-old corpses produce a positive immunoreaction towards thyroglobulin hi all cases whereas none of the corpses older than 13 days show such a reaction. This means that in case of a negative Immunoreaction the time of death can be assumed to lie more than 6 days before the autopsy. The fact that a negative immunoreaction occurrs consistently after 13 days leads to the conclusion that when thyroglobulin has been stained in a specimen, the death of the respective person must lie a maximum of 12 days earlier, whereby these time-limits may change in considerably different surrounding conditions. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
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