Journal
TETRAHEDRON LETTERS
Volume 41, Issue 23, Pages 4573-4577Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)00695-X
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An efficient synthesis of K-13, a non-competitive inhibitor of ACE I, with an endo biaryl ether bond is described. The key cycloetherification reaction of linear tripeptide 10 gave 17-membered macrocycle in quantitative yield. (C) 2000 Elsevier Science Ltd. All rights reserved.
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