Journal
ORGANIC LETTERS
Volume 2, Issue 12, Pages 1725-1727Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol005873c
Keywords
-
Categories
Ask authors/readers for more resources
[GRAPHICS] A DNA-binding dye, 4',6-diamidino-2-phenylindole (DAPI) signals AT base pairing with a shift in the fluorescence emission spectrum. The signaling follows W-C base-pairing rules, and both dAMP and dTMP are required for the largest spectral shift. Thus, the dye with its two phosphate receptor sites functions as a molecular NAND gate accepting nucleotides as inputs. Moreover, when the observation wavelength is changed from 470 to 411.5 nm, the gate functions in TRANSFER logic.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available