Journal
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
Volume 24, Issue 7, Pages 1020-1026Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00000478-200007000-00015
Keywords
extraskeletal myxoid chondrosarcoma neuroendocrine differentiation; histochemistry; immunohistochemistry; ultrastructure; t(9;17)(q22;q11.2); CHN; RBP56/hTAF(II)68
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A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.
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