Journal
CLINICAL INFECTIOUS DISEASES
Volume 31, Issue 1, Pages 76-79Publisher
UNIV CHICAGO PRESS
DOI: 10.1086/313936
Keywords
-
Categories
Funding
- NICHD NIH HHS [N01-HD-4-3214, N01-HD-4-3215, N01-HD-4-3217] Funding Source: Medline
Ask authors/readers for more resources
Antibiotic susceptibility profiles were analyzed for 119 invasive and 227 colonizing strains of group B streptococci isolated from neonates at 6 US academic centers, All strains were susceptible to penicillin, vancomycin, chloramphenicol, and cefotaxime, The rate of resistance to erythromycin was 20.2% and to clindamycin was 6.9%. Resistance to erythromycin increased in 1997, Type V strains were more resistant to erythromycin than were type Ia (P = .003) and type Tb (P = .004) strains and were more resistant to clindamycin than were type Ia (P < .001), type Tb (P = .01), and type III (P = .001) strains. Resistance rates varied with geographic region: in California, there were high rates of resistance to erythromycin and clindamycin (32% and 12%, respectively), and low rates in Florida (8.5% and 2.1%, respectively). Penicillin continues to be the drug of choice for treatment of group B streptococcus infection. For women who are penicillin intolerant, however, the selection of an alternative antibiotic should be guided by contemporary resistence patterns observed in that region.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available