Journal
ACCOUNTS OF CHEMICAL RESEARCH
Volume 33, Issue 7, Pages 503-510Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ar990073r
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Chromium is an essential trace element for mammals and is required for maintenance of proper carbohydrate and lipid metabolism. However, elucidating its function at a molecular level has proved to be problematic. Recent research has revealed that the chromium-binding oligopeptide chromodulin may play a unique role in the autoamplification of insulin signaling. Attempts to develop chromium-containing nutritional supplements and therapeutics are described.
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