Journal
PLANTA
Volume 211, Issue 2, Pages 182-190Publisher
SPRINGER VERLAG
DOI: 10.1007/s004250000283
Keywords
Arabidopsis (farnesylation, mutant); farnesylation; lipid modification; meristem development; mutant (Arabidopsis, farnesylation); photoperiod
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Although studies in plant and animal cell culture systems indicate farnesylation is required for normal cell cycle progression, how this lipid modification of select proteins translates into whole-organism developmental decisions involving cell proliferation or differentiation is largely unknown. The era1 mutant of the higher plant Arabidopsis thaliana (L.) Heynh. offers a unique opportunity to understand the role farnesylation may play in regulating various processes during the development of a multicellular organism. Loss of farnesylation affects many aspects of Arabidopsis growth and development. In particular, epical and axillary meristem development is altered and these phenotypes are contingent on the growth conditions.
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