4.6 Review

The physiological roles of autophagy in the mammalian life cycle

Related references

Note: Only part of the references are listed.
Article Biology

Aberrant regulation of autophagy in mammalian diseases

Wei Xie et al.

BIOLOGY LETTERS (2018)

Review Medicine, Research & Experimental

Autophagy in health and disease: A comprehensive review

Sarbari Saha et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Immunology

Autophagy dysfunction in autoinflammatory diseases

Yichao Hua et al.

JOURNAL OF AUTOIMMUNITY (2018)

Review Endocrinology & Metabolism

Targeting autophagy in obesity: from pathophysiology to management

Yingmei Zhang et al.

NATURE REVIEWS ENDOCRINOLOGY (2018)

Review Cell Biology

Autophagy and its implication in human oral diseases

Ya-Qin Tan et al.

AUTOPHAGY (2017)

Article Multidisciplinary Sciences

Autophagy maintains the metabolism and function of young and old stem cells

Theodore T. Ho et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1

Pinglei Liu et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Cell Biology

Autophagy and Tumor Metabolism

Alec C. Kimmelman et al.

CELL METABOLISM (2017)

Review Cell Biology

Modulation of inflammation by autophagy: Consequences for human disease

Romana T. Netea-Maier et al.

AUTOPHAGY (2016)

Article Biochemistry & Molecular Biology

Atg13 Is Essential for Autophagy and Cardiac Development in Mice

Takeshi Kaizuka et al.

MOLECULAR AND CELLULAR BIOLOGY (2016)

Review Pediatrics

Autophagy in renal diseases

Stephanie De Rechter et al.

PEDIATRIC NEPHROLOGY (2016)

Article Cell Biology

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

Alejandro Vazquez-Martin et al.

AGING-US (2016)

Review Biochemistry & Molecular Biology

Mammalian Autophagy: How Does It Work?

Carla F. Bento et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)

Article Biochemistry & Molecular Biology

Autophagic response to cell culture stress in pluripotent stem cells

Sian Gregory et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Role of Class III phosphoinositide 3-kinase in the brain development: possible involvement in specific learning disorders

Yutaka Inaguma et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Article Multidisciplinary Sciences

Autophagy maintains stemness by preventing senescence

Laura Garcia-Prat et al.

NATURE (2016)

Article Multidisciplinary Sciences

Autophagy and ubiquitin-proteasome system contribute to sperm mitophagy after mammalian fertilization

Won-Hee Song et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Cell & Tissue Engineering

Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells

Areechun Sotthibundhu et al.

STEM CELL RESEARCH & THERAPY (2016)

Article Cell Biology

Autophagy is Required for the Maintenance of Liver Progenitor Cell Functionality

Yiji Cheng et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)

Review Medicine, Research & Experimental

Autophagy in cardiovascular biology

Sergio Lavandero et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Veterinary Sciences

Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation

Masato Hiyama et al.

JOURNAL OF VETERINARY MEDICAL SCIENCE (2015)

Article Multidisciplinary Sciences

Coordination of mitophagy and mitochondrial biogenesis during ageing in C-elegans

Konstantinos Palikaras et al.

NATURE (2015)

Article Multidisciplinary Sciences

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

Pekka Katajisto et al.

SCIENCE (2015)

Review Cell Biology

Historical landmarks of autophagy research

Yoshinori Ohsumi

CELL RESEARCH (2014)

Article Cell Biology

Atg7 is required for acrosome biogenesis during spermatogenesis in mice

Hongna Wang et al.

CELL RESEARCH (2014)

Article Biochemistry & Molecular Biology

Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex

Shukun Wang et al.

EMBO REPORTS (2014)

Article Biochemistry & Molecular Biology

A Cluster of Thin Tubular Structures Mediates Transformation of the Endoplasmic Reticulum to Autophagic Isolation Membrane

Takefumi Uemura et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Article Biochemistry & Molecular Biology

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12-5-16L1

Hannah C. Dooley et al.

MOLECULAR CELL (2014)

Review Endocrinology & Metabolism

Autophagy-a key player in cellular and body metabolism

Kook Hwan Kim et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Article Multidisciplinary Sciences

Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor

Thomas R. Gawriluk et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

The Crucial Role of Atg5 in Cortical Neurogenesis During Early Brain Development

Xiaohui Lv et al.

SCIENTIFIC REPORTS (2014)

Article Cell Biology

ATG5 regulates plasma cell differentiation

Kara L. Conway et al.

AUTOPHAGY (2013)

Review Obstetrics & Gynecology

The role of autophagy in reproduction from gametogenesis to parturition

Tomi T. Kanninen et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2013)

Article Oncology

Autophagy is required for IL-2-mediated fibroblast growth

Rui Kang et al.

EXPERIMENTAL CELL RESEARCH (2013)

Article Cell Biology

Autophagy appears during the development of the mouse lower first molar

Jing-wen Yang et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

FOXO3A directs a protective autophagy program in haematopoietic stem cells

Matthew R. Warr et al.

NATURE (2013)

Article Multidisciplinary Sciences

Functional interaction between autophagy and ciliogenesis

Olatz Pampliega et al.

NATURE (2013)

Article Immunology

Plasma cells require autophagy for sustainable immunoglobulin production

Niccolo Pengo et al.

NATURE IMMUNOLOGY (2013)

Article Neurosciences

FIP200 is required for maintenance and differentiation of postnatal neural stem cells

Chenran Wang et al.

NATURE NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Autophagy in the Human Placenta throughout Gestation

Tai-Ho Hung et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Unique insights into maternal mitochondrial inheritance in mice

Shi-Ming Luo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Immunology

Autophagy in infection, inflammation and immunity

Vojo Deretic et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Article Biochemistry & Molecular Biology

Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes

Ximena Bustamante-Marin et al.

APOPTOSIS (2012)

Review Cell & Tissue Engineering

Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal

Jin Zhang et al.

CELL STEM CELL (2012)

Article Endocrinology & Metabolism

Hypoxia Induces Autophagy in Primary Human Trophoblasts

Baosheng Chen et al.

ENDOCRINOLOGY (2012)

Article Agriculture, Dairy & Animal Science

Autophagy Influences Maternal mRNA Degradation and Apoptosis in Porcine Parthenotes Developing In Vitro

Yong-Nan Xu et al.

JOURNAL OF REPRODUCTION AND DEVELOPMENT (2012)

Article Cell & Tissue Engineering

Basal Autophagy Decreased During the Differentiation of Human Adult Mesenchymal Stem Cells

Lisa Oliver et al.

STEM CELLS AND DEVELOPMENT (2012)

Review Cell Biology

The Role of Atg Proteins in Autophagosome Formation

Noboru Mizushima et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)

Review Biochemistry & Molecular Biology

Autophagy: Renovation of Cells and Tissues

Noboru Mizushima et al.

Review Cell Biology

Autophagy in the Cellular Energetic Balance

Rajat Singh et al.

CELL METABOLISM (2011)

Article Endocrinology & Metabolism

Autophagy Regulates Embryonic Survival During Delayed Implantation

Jong-Eun Lee et al.

ENDOCRINOLOGY (2011)

Editorial Material Obstetrics & Gynecology

Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells

JongYeob Choi et al.

FERTILITY AND STERILITY (2011)

Article Immunology

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

Monika Mortensen et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Autophagy in Human Embryonic Stem Cells

Thien Tra et al.

PLOS ONE (2011)

Article Developmental Biology

Autophagy is a cell survival program for female germ cells in the murine ovary

Thomas R. Gawriluk et al.

REPRODUCTION (2011)

Article Biochemistry & Molecular Biology

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

Dale W. Hailey et al.

Article Obstetrics & Gynecology

The role of autophagy in follicular development and atresia in rat granulosa cells

Jong Yeob Choi et al.

FERTILITY AND STERILITY (2010)

Article Biochemistry & Molecular Biology

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

Deepak Adhikari et al.

HUMAN MOLECULAR GENETICS (2010)

Review Biochemistry & Molecular Biology

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

Shomit Sengupta et al.

MOLECULAR CELL (2010)

Review Genetics & Heredity

Regulation Mechanisms and Signaling Pathways of Autophagy

Congcong He et al.

ANNUAL REVIEW OF GENETICS (2009)

Article Cell Biology

Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy

Nao Hosokawa et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Cell Biology

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Cell Biology

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

Mitsuko Hayashi-Nishino et al.

NATURE CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

Chong Chen et al.

SCIENCE SIGNALING (2009)

Review Pathology

Autophagy: Basic principles and relevance to disease

Mondira Kundu et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)

Article Cell Biology

The role of autophagy during the oocyte-to-embryo transition

Satoshi Tsukamoto et al.

AUTOPHAGY (2008)

Article Cell Biology

Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery

Enko N. Kiprilov et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Autophagy and endocytosis in the amnion

Zhong-Ying Shen et al.

JOURNAL OF STRUCTURAL BIOLOGY (2008)

Article Developmental Biology

Autophagic and Apoptotic Cell Death in Amniotic Epithelial Cells

Z. -Y. Shen et al.

PLACENTA (2008)

Article Multidisciplinary Sciences

Autophagy is essential for preimplantation development of mouse embryos

Satoshi Tsukamoto et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

Takao Hanada et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig et al.

NATURE (2007)

Article Multidisciplinary Sciences

Developmental reprogramming after chromosome transfer into mitotic mouse zygotes

Dieter Egli et al.

NATURE (2007)

Review Multidisciplinary Sciences

Regulation of the oocyte-to-zygote transition

Michael L. Stitzel et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Autophagy gene-dependent clearance of apoptotic cells during embryonic development

Xueping Qu et al.

Article Cell Biology

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

Shida Yousefi et al.

NATURE CELL BIOLOGY (2006)

Article Cell Biology

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

M Komatsu et al.

JOURNAL OF CELL BIOLOGY (2005)

Article Multidisciplinary Sciences

The role of autophagy during the early neonatal starvation period

A Kuma et al.

NATURE (2004)

Review Developmental Biology

Embryonic diapause and its regulation

FL Lopes et al.

REPRODUCTION (2004)

Article Multidisciplinary Sciences

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

ZY Yue et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Cell Biology

Autophagy in embryonic erythroid cells: its role in maturation

H Takano-Ohmuro et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2000)