Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 66, Issue 1-3, Pages 25-27Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/S0925-4005(99)00452-9
Keywords
glucose sensors; electropolymerization; pyrrole derivatives; hemocompatible polymer; phosphatidylcholine
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New hemocompatible glucose sensors were prepared by electropolymerization of pyrrole derivatives having phosphatidylcholine, 5-(1-pyrrolyl)pentyl-2-(trimethylammonium)ethyl phosphate, in the presence of glucose oxidase (GOD), with an inner-membrane of Nafion or poly(o-phenylenediamine) (PPD). The introduction of these membranes not only eliminated the influence of ascorbic acid on the sensor response but also increased the electrode stability. The electrode responses containing PPD inner-membrane were shown to be relatively constant for more than 200 days or three times as long as the electrode responses without the inner membranes. (C) 2000 Elsevier Science S.A. All rights reserved.
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