Journal
CATALYSIS TODAY
Volume 60, Issue 3-4, Pages 305-309Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0920-5861(00)00347-3
Keywords
multicomponent reactions; reactions in water; clays; environmental protection
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Three-component reactions for the synthesis of substituted dihydropyrimidines (4), chromenes (8) and tetrahydroquinolines (11) have been performed in water and in the presence of a montmorillonite KSF clay. The products, easily isolated from the reaction mixture by crystallisation, are obtained in high yield and selectivity and the catalyst can be recycled for many runs without losing its activity. (C) 2000 Elsevier Science B.V. All rights reserved.
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