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Facile synthesis of chiral isopropyl carbinols with high enantiomeric excess via catalytic enantioselective addition of diisopropylzinc to aldehydes

TETRAHEDRON-ASYMMETRY (2000)

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Journal

TETRAHEDRON-ASYMMETRY
Volume 11, Issue 14, Pages 2947-2953

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0957-4166(00)00253-6

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Categories

Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry, Physical

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Highly effective syntheses of chiral alkyl and aryl isopropyl carbinols with high enantiomeric excess (94-98% ec) via catalytic enantioselective addition of diisopropylzinc to aldehydes have been developed. (C) 2000 Elsevier Science Ltd. All rights reserved.

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