Journal
BRAIN RESEARCH
Volume 872, Issue 1-2, Pages 236-241Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0006-8993(00)02493-8
Keywords
Bcl-2; talipexole; pramipexole; regeneration
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Treatment of rats for 4 days with the antiparkinsonian drugs, talipexole and pramipexole, markedly increased Bcl-2 immunoreactivity in neuronal dendritic processes in both cerebral cortex and hippocampus, but treatment for 1 day with either of these drugs did not. Repeated administration of talipexole or pramipexole may have neuroprotective effect in neurodegenerative disorders. (C) 2000 Elsevier Science B.V. An rights reserved.
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