Journal
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1467, Issue 1, Pages 198-206Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0005-2736(00)00221-2
Keywords
diphytanoyl phosphatidylcholine bilayer; dimyristoyl phosphatidylcholine; X-ray diffraction; phase transition; headgroup energetics; chain energetics
Categories
Funding
- NIGMS NIH HHS [GM55203] Funding Source: Medline
Ask authors/readers for more resources
A comparative study on bilayers of diphytanoyl phosphatidylcholine (DPhPC) and bilayers of dimyristoyl phosphatidylcholine (DMPC) was made by X-ray lamellar diffraction as a function of temperature and the degree of hydration. An order-disorder phase transition of DPhPC reveals an interesting contrast to the standard model of DMPC. Electron density profiles allow us to deduce the conformational changes which occur in the headgroup-glycerol region and in the chain region. The important conclusion is that the lipid headgroup may have different conformational energetics in lipids of different chains. We explain why this is important to protein-membrane interactions. (C) 2000 Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available