Journal
BIOTECHNOLOGY LETTERS
Volume 22, Issue 15, Pages 1211-1216Publisher
SPRINGER
DOI: 10.1023/A:1005603117023
Keywords
combinatorial library; crystal; peptide; phage display; recognition
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The feasibility of using a combinatorial phage display library of decapeptides to identify ligands which can interact with the surface of a crystal was assessed using geological calcium carbonate as a model. Two relatively strong binding clones were identified by ELISA, sequenced and the encoded oligopeptides were prepared by solid phase synthesis and their properties compared with those of casein hydrolysate.
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