Journal
JOURNAL OF VIROLOGY
Volume 74, Issue 16, Pages 7694-7697Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.74.16.7694-7697.2000
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Funding
- NIAID NIH HHS [R01 AI028568, R37 AI028568, AI28568, R01 AI030914, AI30914] Funding Source: Medline
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Respiratory syncytial virus (RSV) infection is a major cause of morbidity in childhood worldwide. The first human RSV-specific cytotoxic T-lymphocyte epitope to be defined is described. This HLA B7-restricted epitope in nucleoprotein (NP) was detectable in four healthy, B7-positive adult subjects using B7-RSV-NP tetrameric complexes to stain CD8+ T cells.
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