Journal
IMMUNOLOGY TODAY
Volume 21, Issue 8, Pages 371-378Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0167-5699(00)01667-4
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In the past decade, the drive to develop completely human antibodies for human therapy has led to the development of phage display technology. This technology is able to deliver the ultimate in antibody engineering, that is, high-affinity fully human antibodies to any antigen of choice. Here, this application of phage display technology is reviewed, and the many other antibody-engineering avenues this technology offers are highlighted.
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