Journal
JOURNAL OF COMPARATIVE PATHOLOGY
Volume 123, Issue 2-3, Pages 210-217Publisher
ELSEVIER SCI LTD
DOI: 10.1053/jcpa.2000.0407
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Multiple endocrine neoplasms, including an insulinoma, bilateral adrenocortical adenocarcinomas and an aortic paraganglioma, were diagnosed after euthanasia in a 12-year-old spayed female dog of mixed breed with a history of progressive anorexia, vomiting, diarrhoea, weight loss, polyuria and polydipsia, regenerative anaemia and hypoglycaemia. The clinical, gross pathological, microscopical, immunohistochemical and ultrastructural findings were consistent with the human syndrome of multiple endocrine neoplasia. (C) 2000 Harcourt Publishers Ltd.
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