The importance of quality-of-life endpoints in clinical trials to the practicing oncologist

Quality-of-life research has helped to describe and draw attention to the human side of cancer treatment. The practicing oncologist can learn a great deal by keeping abreast of developments in this field and using these findings in treatment decision making. This article traces the change in the cancer disease experience as a context for understanding the importance of quality-of-life research. The history of quality-of-life research and measurement is examined, and this information is integrated into a practical discussion of physician-patient communication.