Journal
BIOLOGICAL PSYCHIATRY
Volume 64, Issue 2, Pages 81-88Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.biopsych.2008.01.003
Keywords
cerebellum; cognition; neuroimaging; schizophrenia
Categories
Funding
- NIMH NIH HHS [5 R01 MH060990-09, 5 R01 MH 04856-20, R01 MH040856, R01 MH040856-21, R01 MH060990] Funding Source: Medline
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For many years the cerebellum has been considered to serve as a coordinator of motor function. Likewise, for many years schizophrenia has been considered to be a disease that primarily affects the cerebrum. This review summarizes recent evidence that both these views must be revised in the light of emerging evidence about cerebellar function and the mechanisms of schizophrenia. Evidence indicating that the cerebellum plays a role in higher cortical functions is summarized. Evidence indicating that cerebellar abnormalities occur in schizophrenia is also reviewed. These suggest interesting directions for future research.
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