Journal
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
Volume 11, Issue 4, Pages -Publisher
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/0973-1482.150405
Keywords
Hepatocellular carcinoma; radiofrequency ablation; renal cell carcinoma; sorafenib
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The combination of renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC) is extremely rare, and the prognosis for patients with these two cancers is poor. In the past decade, molecular targeted therapy and radiofrequency ablation (RFA) have emerged and these treatments are now playing an increasingly important role in the management of patients with advanced primary RCC and HCC. In this case report, a 72-year-old male patient diagnosed as having RCC invading the renal vein and grade I-II HCC was treated with RFA and sorafenib (400 mg twice daily). After 3 months of this combination treatment, an evaluation of his target lesions showed stable disease (SD), and progression-free survival (PFS) times were 28 monthsweeks for RCC and 16 monthsweeks for HCC. Overall survival (OS) was 40 weeks.
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