Journal
PROTEIN SCIENCE
Volume 9, Issue 8, Pages 1594-1600Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1110/ps.9.8.1594
Keywords
L6; superfamily; tetraspanin
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L6, IL-TMP, and TM4SF5 are cell surface proteins predicted to have four transmembrane domains. Previous sequence analysis led to their assignment as members of the tetraspanin superfamily. In this paper, we identify a new sequence (L6D) that is strikingly similar to L6, IL-TMP, and TM4SF5. Analyses of these four sequences indicate that they are not significantly related to genuine tetraspanins, but instead constitute their own L6 superfamily.
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