4.4 Article

Differential infectivity and division of Toxoplasma gondii in human peripheral blood leukocytes

Journal

INFECTION AND IMMUNITY
Volume 68, Issue 8, Pages 4822-4826

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.68.8.4822-4826.2000

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Funding

  1. NCI NIH HHS [CA 23108, P30 CA023108] Funding Source: Medline
  2. NIAID NIH HHS [R01 AI019613, AI30000, AI19613] Funding Source: Medline

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When tachyzoites were incubated with human peripheral blood leukocytes in vitro, more monocytes and dendritic cells than neutrophils or lymphocytes were infected. Although tachyzoites were able to divide in each of these cell types, monocytes and dendritic cells were more permissive to rapid tachyzoite division than neutrophils or lymphocytes.

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