☆ 4.5 Article

Synthesis of aminophosphonate haptens for an aminoacylation reaction between methyl glucoside and a β-alanyl ester

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)

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Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 10, Issue 15, Pages 1749-1750

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(00)00328-0

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Categories

Chemistry, Medicinal Chemistry, Organic

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Two 2-aminophosphonate haptens derived from methyl alpha-D-glucopyranoside were synthesized to mimic the transition-state of a transesterification reaction between methyl alpha-D-glucopyranoside and 3-nitrophenylester of tert-BOC-beta-alanine. Two sets of monoclonal antibodies were generated against these haptens. (C) 2000 Elsevier Science Ltd. All rights reserved.

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