4.5 Article

Production and application of LPA polyclonal antibody

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 10, Issue 15, Pages 1691-1693

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(00)00325-5

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By using colloidal gold as a hapten carrier, a kind of antibody against lysophosphatidic acid (LPA) was developed and used to successfully detect 500 ng/mL LPA in dot immunogold filtration assay. Such application of the LPA antibody could offer us a way to diagnose ovarian cancer at its early stage. (C) 2000 Elsevier Science Ltd. All rights reserved.

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