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Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amido ketones

TETRAHEDRON-ASYMMETRY (2000)

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Journal

TETRAHEDRON-ASYMMETRY
Volume 11, Issue 16, Pages 3257-3261

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0957-4166(00)00310-4

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Categories

Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry, Physical

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A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of alpha-amido ketones, is described. (C) 2000 Elsevier Science Ltd. All rights reserved.

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