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Asymmetric synthesis of (R)-(+)-etomoxir via enzymatic resolution

Journal

TETRAHEDRON-ASYMMETRY
Volume 11, Issue 16, Pages 3395-3401

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0957-4166(00)00304-9

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An asymmetric synthesis of (R)-(+)-etomoxir 3, employing enzymatic resolution of ethyl 2-alkyl-2,3dihydroxypropionate using Amano AK via transacylation is reported. (C) 2000 Elsevier Science Ltd. All rights reserved.

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