Journal
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Volume 67, Issue 1, Pages 25-28Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0091-3057(00)00291-4
Keywords
ACTH; beta-endorphin; cortisol; smoking; cigarettes consumed per day
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The harmful effects of smoking on health have been widely documented, although it is as yet unclear whether tobacco dependence is only psychological in nature, or both psychological and physical. We studied plasma concentrations of beta-endorphin, cortisol, and adrenocorticotropic hormone (ACTH) in healthy persons who consumed different numbers of cigarettes per day, and compared the findings with those in a control group of nonsmokers. Beta-endorphin levels were significantly higher than in controls only in persons who smoked fewer than 10 cigarettes per day. Cortisol levels were significantly higher in smokers who consumed more than 20 cigarettes per day. There were no significant differences between any of the groups in plasma ACTH concentrations. (C) 2000 Elsevier Science Inc. All rights reserved.
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