4.8 Article

Inter- and intramolecular reductive coupling reactions: An approach to the phorbol skeleton

Journal

ORGANIC LETTERS
Volume 2, Issue 18, Pages 2873-2876

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol006301v

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An expeditious convergent route to the ABC-tricyclic core of the phorbol esters is described, The chemistry capitalizes upon both inter- and intramolecular reductive coupling processes promoted electrochemically and via the use of samarium diiodide.

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