Journal
JOURNAL OF PHYSICAL CHEMISTRY B
Volume 104, Issue 37, Pages 8903-8910Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jp0019658
Keywords
-
Categories
Ask authors/readers for more resources
A mechanism for selectivity of calcium over sodium in a biological channel is studied by means of a Monte Carlo simulation. This model channel is an infinite cylinder containing negatively charged glutamates, each modeled as a pair of half charged oxygens, and an electrolyte. The fluid in the channel is in equilibrium with a bulk electrolyte. The proportion of Ca2+ ions in the channel is greatly in excess of that in the bulk because, in the restricted space in the channel, the doubly charged Ca2+ ions require less volume and are more effective at neutralizing the charge of glutamates than twice the number of singly charged Na+ ions with the same amount of charge.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available