Journal
LANCET
Volume 356, Issue 9235, Pages 1077-1078Publisher
LANCET LTD
DOI: 10.1016/S0140-6736(00)02733-1
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For many years, ivermectin has been widely distributed throughout west Africa for the safe and effective control of onchocerciasis. However, recent events in Loa-ka-endemic areas of Cameroon, where severe adverse reactions have occurred, now constrain the public-health use of this drug in the forest habitat of the L loa vector. We have created a model of L loa prevalence to identify areas where high endemicity may be associated with the occurrence of such reactions. The model results have been mapped and the areas of overlap between high L loa prevalence and planned ivermectin distribution for onchocerciasis control identified.
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