Journal
JOURNAL OF CHROMATOGRAPHY B
Volume 747, Issue 1-2, Pages 171-202Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0378-4347(00)00154-7
Keywords
reviews; heteroaromatic amines
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In recent years, many studies have dealt with the role of certain heteroaromatic amines (HAs) as mutagenic compounds, and their occurrence in foodstuffs. Here we examine the determination of HAs, focusing on the analytical strategies for their extraction and preconcentration from several matrices. We summarise the properties of heteroaromatic amines and the main drawbacks involved in their analysis, and then concentrate on the separation procedures, sorbents and solvents used in the sample treatment. We discuss the requirements of the analytical techniques and the strategies most frequently followed to achieve accurate results. (C) 2000 Elsevier Science B.V. All rights reserved.
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