Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 43, Issue 4, Pages 571-591Publisher
MOSBY-ELSEVIER
DOI: 10.1067/mjd.2000.107248
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- NIAMS NIH HHS [R29AR41008] Funding Source: Medline
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Cicatricial pemphigoid (CP) is a heterogeneous group of rare, chronic, subepithelial blistering disorders of the mucous membranes and, occasionally the skin, which can have serious and rarely fatal consequences. The most common clinical features are desquamative gingivitis, oral erosions, and conjunctival fibrosis. Skin lesions occur less frequently and may present as widespread vesicles and bullae, as in bullous pemphigoid (BP). In some patients, the scarring can be a source of significant morbidity because it can result in odynophagia, strictures of the upper aerodigestive tract, or corneal opacities lending to eventual blindness. This article is a comprehensive review and discusses clinical, pathologic, and pathophysiologic aspects of this group of disorders collectively known as CP.
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