Journal
JOURNAL OF BACTERIOLOGY
Volume 182, Issue 20, Pages 5902-5905Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.182.20.5902-5905.2000
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An in silico scan of the partially completed genome sequence of Bordetella pertussis and analyses of transcriptional fusions generated with a new integrational vector were used to identify new potential virulence genes. The genes encoding a putative siderophore receptor, adhesins, and an autotransporter protein appeared to be regulated in a manner similar to Bordetella virulence genes by the global virulence regulator BvgAS. In contrast, the gene encoding a putative intimin-like protein appeared to be repressed under conditions of virulence.
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