Journal
INFECTION AND IMMUNITY
Volume 68, Issue 10, Pages 6052-6055Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.68.10.6052-6055.2000
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Funding
- NEI NIH HHS [R01 EY10974, R01 EY010974] Funding Source: Medline
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Alpha-toxin is a major virulence factor in Staphylococcus aureus keratitis. Active or passive immunization with alpha-toxin toroid could protect against corneal damage. Results show that either form of immunization did not kill bacteria but did significantly protect against corneal pathology, especially epithelial erosion.
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