Herbertane-type sesquiterpenoids from the liverwort Herbertus sakuraii

Seven herbertane-type sesquiterpenoids, 1,13-dihydroxyherbertene, 1,1 4-dihydroxyherbertene, 1,15-dihydroxyherbertene, 12-methoxyherebertene-1,2-diol, herberteneacetal, herbertenone A and herbertenone B were isolated from the Japanese liverwort Herbertus sakuraii, together with four known herbertane- and three dimeric herbertane-type sesquiterpenoids and ent-pimara-8(14), 15-dien-19-oic acid. Their structures were elucidated by spectroscopic methods. H. sakluraii is chemically similar not only to H. aduneus but also to the Mastigophora species. (C) 2000 Elsevier Science Ltd. All rights reserved.