Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 44, Issue 10, Pages 2876-2879Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.44.10.2876-2879.2000
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A new high-level gentamicin resistance gene, designated aph(2)-Ib, was cloned from Enterococcus faecium SF11770. The deduced amino acid sequence of the 897-bp open reading frame of aph(2)-Ib shares homology with the aminoglycoside-modifying enzymes AAC(6')APH(2), APH(2)-Ic, and APH(2)-Id. The observed phosphotransferase activity is designated APH(2)-Ib.
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