Histocompatibility antigen (HLA) associations with multiple sclerosis in Iran

Human leukocyte antigen (HLA) types were obtained from 79 Iranian patients with multiple sclerosis and compared with 100 controls. The prevalence of HLA-A24 (30.3% versus 18.0%) HLA-DR2 (43.0% versus 28.0%) and HLA-DRIS (36.7% versus 23.0%) were significantly increased in multiple sclerosis patients compared with controls. However age at onset, and disease status (relapsing-remitting or primary progressive) did not show on association with any particular HLA type.