3.8 Article

Mechanisms of amyloidogenesis

Journal

NATURE STRUCTURAL BIOLOGY
Volume 7, Issue 10, Pages 824-826

Publisher

NATURE AMERICA INC
DOI: 10.1038/82815

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Limitations of the three putative mechanisms of amyloid fibril assembly for explaining Sup35 prion formation have led to the introduction of a fourth model - nucleated conformational conversion - that invokes oligomeric: intermediates for initiation and assembly.

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