Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 12, Issue 5, Pages 634-640Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(00)00143-5
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Funding
- NHLBI NIH HHS [HL28749] Funding Source: Medline
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Considerable progress has been made towards understanding the function of thrombospondin-l and -2. The description of the phenotype of mice with thrombospondin-l and -2 knocked-out supports in vitro biochemical and cell-biological data and has opened new avenues of research. Recently, our understanding of the roles of thrombospondins in the activation of TG F beta, inhibition of angiogenesis and the initiation of signal transduction has advanced.
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