Journal
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Volume 34, Issue 3, Pages 330-334Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/bpb.34.330
Keywords
acidic resistance; OmpC; OmpF; Escherichia coli
Categories
Ask authors/readers for more resources
The roles of OmpC and OmpF in acidic resistance (AR) were examined. When ompC and ompF were deleted, AR was decreased. The decreased level of AR seen in the mutant that was deficient in ompC and ompF was elevated by the addition of glutamate, but not by the addition of arginine or lysine. The expression levels of adiA and cadB were diminished by the deletion of ompC and ompF, and the conversion of arginine to agmatine and lysine to cadaverine by intact cells were reduced in the mutant. The expression of gadA/gadB was not affected by the deletion of ompC and ompF. These results suggest that the transport of arginine, lysine, and their decarboxylated products through OmpC and/or OmpF is essential for the survival of Escherichia coli cells under extremely acidic conditions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available