Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 3, Issue 5, Pages 496-501Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1369-5274(00)00129-6
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The current epidemic of bacterial resistance is attributed, in part, to the overuse of antibiotics. Recent studies have documented increases in resistance with over-use of particular antibiotics and improvements in susceptibility when antibiotic use is controlled. The most effective means of improving use of antibiotics is unknown. Comprehensive management programs directed by multi-disciplinary teams, computer-assisted decision-making, and antibiotic cycling have been beneficial in controlling antibiotic use, decreasing costs without impacting patient outcomes, and possibly decreasing resistance.
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