Journal
IMMUNOLOGY TODAY
Volume 21, Issue 10, Pages 475-478Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0167-5699(00)01715-1
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Funding
- NHLBI NIH HHS [HL04343, HL63339, P50-HL56386] Funding Source: Medline
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Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.
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